The hip-hop star took the stage to rock the crowd at Manhattan's 230 Fifth rooftop bar as part of NBC network's New Year's Eve with Carson Daly - as the TV host counted down the minutes to 2011 from New York.
However, the mishap didn't stop the show - the duo ended the performance by encouraging their fans to put your hands up
Introduced by Nicki Minaj, who called Wayne "the undisputed best rapperalive," Wayne began lyrics to his track 6 Foot 7 Foot, and was joined by his newest protege, Cory Gunz - but their voices couldn't be heard over the music beats and screaming fans.
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However, the mishap didn't stop the show - the duo ended the performance by encouraging their fans to "put your hands up" and Wayne later returned to the stage for a rendition of Right Above It, although the audio issue did not appear to be resolved.
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